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These are just some of the many questions that can be answered with the use of clinical prediction rules. Clinical prediction rules, also known as “prediction algorithms” or “prediction models”, have become increasingly prominent over the past two years and are frequently mentioned in the media. In reality clinical prediction rules have been in use much longer than that, and have a range of applications across many different areas of medicine.

Why have clinical prediction rules become so popular?

An important factor is that we currently live in the era of “big data”, and large, routinely collected datasets that are very rich in information can provide plenty of scope for developing new prediction rules. This in combination with increased computational power has created a very good opportunity for this field to quickly develop and evolve.

But what exactly are clinical prediction rules, and how they can actually help?

In simple terms, a clinical prediction rule is a mathematical equation which combines different characteristics to assess the probability of a particular event happening – such as a patient developing a certain condition in the future. These characteristics can include a variety of information, ranging from basic demographic characteristics to previous medical conditions and treatments. A clinical prediction rule combines all these pieces of information to provide an individualised assessment, which can then inform clinical decision-making.

Generating a clinical prediction rule is however a complex process, which involves many steps and contains many hidden traps. For this reason a new course, Clinical Prediction Rules, will run as a new accredited short course in May 2022.

What does this short course cover?

This course will cover all aspects of clinical prediction rule studies, from design and model development to interpretation and validation. By the end of the course, students will have acquired knowledge of the key concepts relevant to each of these areas, and should be confident to conduct a clinical prediction rule study themselves and appraise existing clinical prediction rules in the medical literature.

This course will be led by Dr Tom Fanshawe ( and Dr Constantinos Koshiaris (, supported by other teaching and research staff from the Nuffield Department of Primary Care Health Sciences.

It will run as an accredited short course in May 2022. It will also be available for students who join the MSc in Evidence Based Health Care Medical Statistics from academic year 2022/23, and so provides an ideal stepping-stone for students who are considering applying to that programme.

How can I apply?

For more information, and to apply, visit:

Students considering applying for the MSc in Evidence Based Health Care Medical Statistics can find more information at: