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January 2012

Underpinning research published

Heneghan C, Ward A, Perera R, Bankhead C, Fuller A, Stevens R, Bradford K, Tyndel S, Alonso-Coello P, Ansell J, Beyth R. 
Self-monitoring of oral anticoagulation: systematic review and meta-analysis of individual patient data.
The Lancet. 2012 Jan 28;379(9813):322-34.

Funded by the National Institute of Health Research, included a meta-analysis of individual participant data involving over 30 international collaborators (“Self-Monitoring Triallist Collaboration”). The Individual patient data analysis, with 12,800 person-years of follow-up, showed that self-monitoring was effective in the long term and across a wide age range of participants.

February 2012


Evidence-Based Management of Anticoagulant Therapy Antithrombotic
Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines – cites 2006 self monitoring review, 2011 Lancet review and 2010 optimal loading dose review. These guidelines remain the current version.

April 2012

Underpinning research published

Mahtani KR, Heneghan CJ, Nunan D, Bankhead C, Keeling D, Ward AM, Harrison SE, Roberts NW, Hobbs FDR, Perera R.
Optimal loading dose of warfarin for the initiation of oral anticoagulation.
Cochrane Database of Systematic Reviews 2012 Issue 12. Art. No.: CD008685.
DOI: 10.1002/14651858.CD008685.pub2.

November 2012

Underpinning research published

Plüddemann A, Thompson M, Wolstenholme J, Price CP, Heneghan C.
Point-of-care INR coagulometers for self-management of oral anticoagulation: primary care diagnostic technology update.
Br J Gen Pract. 2012 Nov 1;62(604):e798-800.