Research
We bring together a multidisciplinary team and aim to be a source of high-quality evidence on which clinical decisions can be reliably based.
Our flagship projects
COVID-19 Evidence Service
Rapid evidence reviews, data analysis and thought-provoking writing on the coronavirus pandemic, updated regularly by our team with international collaborators. Our reviews have informed international policy and media reporting.
Transmission dynamics of COVID-19
One of the principal uncertainties regards the means by which COVID-19 is transmitted. Our open evidence approach analyses the transmission dynamics of COVID-19 and includes evidence searches, research summaries and more.
Primodos & congenital malformations
Oral hormone pregnancy tests were given to over a million women in 20th Century, until they were withdrawn over safety concerns. Our systematic review uncovers a link between Primodos and congenital malformation.
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Can Tamiflu treat influenza?
Since 2014, the CEBM have been conducting research about the effects of neuraminidase inhibitors for treating symptoms of influenza. These activities have led to important changes in health policy and clinical practice.
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The harms of transvaginal mesh
In 2014 Professor Carl Heneghan joined an undercover investigation to expose how the regulation of medical devices is so lax that mesh packaging for fruit could be approved as a medical device to be implanted in people’s bodies.
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Image by allinonemovie from Pixabay
What is the best anticoagulation care?
CEBM researchers are leading research to optimise the use of anticoagulants. The work includes a suite of systematic reviews, several of which have influenced national and international health policy and clinical guidelines.
Current research
Our multidisciplinary research team are undertaking several different research projects.
Key research papers
Overdiagnosis: what it is and what it isn't
Journal article
Brodersen J. et al, (2018), BMJ evidence-based medicine, 23, 1 - 3
Ten essential papers for the practice of evidence-based medicine
Journal article
Nunan D. et al, (2017), Evidence-Based Medicine, 22, 202 - 204
Effect of oral dexamethasone without immediate antibiotics vs placebo on acute sore throat in adults a randomized clinical trial
Journal article
Hayward GN. et al, (2017), JAMA - Journal of the American Medical Association, 317, 1535 - 1543
Neuraminidase inhibitors for influenza: A systematic review and meta-analysis of regulatory and mortality data
Journal article
Heneghan CJ. et al, (2016), Health Technology Assessment, 20, 1 - 242
Neuraminidase inhibitors for preventing and treating influenza in children
Journal article
Matheson NJ. et al, (2007), Cochrane Database of Systematic Reviews
Does cranberry extract reduce antibiotic use for symptoms of acute uncomplicated urinary tract infections (CUTI)? Protocol for a feasibility study
Journal article
Gbinigie O. et al, (2019), Trials, 20
Latest publications
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Introducing the BMJ EBM series: Coroners’ Concerns to Prevent Harms - A series of coroners’ case reports to serve patient safety and educate the public, clinicians, and policymakers
Journal article
Richards G. et al, (2020), BMJ Evidence Based Medicine
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Lost in reviews: Looking for the involvement of stakeholders, patients, public and other non-researcher contributors in realist reviews
Journal article
Abrams R. et al, (2020), Research Synthesis Methods
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Risk of adverse COVID-19 outcomes for people living with HIV: a rapid review and meta-analysis
Journal article
Mellor M. et al, (2020)
The Centre for Evidence Based Medicine currently receives no core funding. Like most academic organisations, we fund the majority of our research from grants won through open competition.
We neither seek nor accept funding for our research from pharmaceutical companies or other private enterprises with relevant conflicts of interest.
Contact us
Centre for Evidence-Based Medicine
Nuffield Department of Primary Care Health Sciences
Radcliffe Primary Care Building, University of Oxford
Woodstock Road, Oxford
OX2 6GG
T: +44 (0)1865 289322
E: Ruth Davis, CEBM Operations & Centre Manager - ruth.davis@phc.ox.ac.uk