SAVE the DATE. The Evidence based diagnosis 2027 (EBeD27) conference will bring together leading, academics, entrepreneurs, regulators and policy makers, together with patient and public representatives to discuss evidence-based diagnosis. We will endeavour to balance the promise offered by technologically and AI driven innovative diagnostics with the need to make progress in a way which is safe, evidence based and patient centred. The event will be participative and interactive with the aim of progressing an agreed development and implementation optimal pathway for new diagnostics. Hosted in the attractive and historic costal university town of St Andrews the event will be co-sponsored by the University of St Andrews, the Centre for Evidence-Based Medicine at the University of Oxford, the University of Birmingham and by the British Medical Journal. The event builds on a highly successful initial meeting in 2024.