A physical map of 30,000 human genes
Deloukas P., Schuler GD., Gyapay G., Beasley EM., Soderlund C., Rodriguez-Tomé P., Hui L., Matise TC., McKusick KB., Beckmann JS., Bentolila S., Bihoreau MT., Birren BB., Browne J., Butler A., Castle AB., Chiannilkulchai N., Clee C., Day PJR., Dehejia A., Dibling T., Drouot N., Duprat S., Fizames C., Fox S., Gelling S., Green L., Harrison P., Hocking R., Holloway E., Hunt S., Keil S., Lijnzaad P., Louis-Dit-Sully C., Ma J., Mendis A., Miller J., Morissette J., Muselet D., Nusbaum HC., Peck A., Rozen S., Simon D., Slonim DK., Staples R., Stein LD., Stewart EA., Suchard MA., Thangarajah T., Vega-Czarny N., Webber C., Wu X., Hudson J., Auffray C., Nomura N., Sikela JM., Polymeropoulos MH., James MR., Lander ES., Hudson TJ., Myers RM., Cox DR., Weissenbach J., Boguski MS., Bentley DR.
A map of 30,181 human gene-based markers was assembled and integrated with the current genetic map by radiation hybrid mapping. The gene map contains nearly twice as many genes as the previous release, includes most genes that encode proteins of known function, and is twofold to threefold more accurate than the previous version. A redesigned, more informative and functional World Wide Web site (www.ncbi.nlm.nih.gov/genemap) provides the mapping information and associated data and annotations. This resource constitutes an important infrastructure and tool for the study of complex genetic traits, the positional cloning of disease genes, the cross- referencing of mammalian genomes, and validated human transcribed sequences for large-scale studies of gene expression.