Evidence-based thinking and why it matters. Views expressed represent the views of the author and not necessarily those of CEBM as a group.
When electronic cigarettes (e-cigarettes) first emerged, they became a popular way for people to quit smoking. But in 2019, a mysterious lung condition emerged that primarily affected young people, particularly those who vaped. This left many questioning the safety of e-cigarettes.
COVID: the reason cases are rising among the double vaccinated – it’s not because vaccines aren’t working
Sir Patrick Vallance, the UK’s chief scientific adviser, has announced that 40% of people admitted to hospital with COVID in the UK have had two doses of a coronavirus vaccine. At first glance, this rings very serious alarm bells, but it shouldn’t. The vaccines are still working very well.
DPhil student Georgia Richards argues why it’s time for doctors to rethink the prescribing of high-dose opioids for people with chronic pain.
People with type 1 diabetes are approximately 3.5 times as likely to die in hospital with COVID-19, while people with type 2 are approximately twice as likely, but why is this, and what can be done to reduce this risk?
We are unlikely to know whether nicotine replacement has a role in COVID-19 any time soon. For now, nicotine supplies must be preserved for the people who need them.
28 October 2019
Realist reviews are becoming an increasing popular approach to synthesising evidence about complex interventions. Whilst Geoff welcomes this increase, he raises challenges that such popularity might bring
J Mark Riddell
31 July 2019
Charles II was born on 29 May 1630 to Charles I and his French wife, Henrietta Maria, and died on 6 February 1685. Here Jeff Aronson describes Charles’s final illness and suggests that his death was hastened by his doctors.
The long-term use of opioids for pain: what’s the problem? People receiving long-term pain relief for low back pain gain no benefits from opioids. Georgia Richards discusses her research on why this might be the case.
We have put together an exhibition of the Kings and Queens, their illnesses, their deaths, and the public health messages their stories portray. The messages include preventable diseases such as obesity, smoking, and vaccination for smallpox, along with the problems of overtreatment, its consequences and its effect on speeding up the death of some of the monarchs. Carl Heneghan, Director Centre for Evidence-Based Medicine
17 July 2017
Early CGM devices were expensive and had problems with accuracy and reliability, and patients often needed to provide finger-prick data to keep them. Modern CGMs are smaller and cheaper, but are they reliable?
12 January 2017
Jeremy Howick discusses whether it is ethical for clinicians to recommend that their patients sign up for a trial, even if there is an established therapy.
How might we increase research efficiency?